Sub-Saharan Africa remains one of the worst affected areas for HIV/AIDS across the world. As of 2013, 71% of the global total of HIV patients came from this region.  This means 24.7 million living with HIV, a prevalence rate of 4.7% and 39% of adults in some form of ART.

Within this wider region, it is South Africa that has the largest epidemic and Swaziland with the highest prevalence of 27.4%.

This is of great concern in HIV prevention due to local contributing factors and obstacles. This is why organizations such as Avert are so important.